Codeine and promethazine is a combination medicine applied to take care of cold or allergy signs which include runny nose, sneezing, and cough.
Very carefully measure the dose using a Distinctive measuring gadget/spoon. Will not make use of a home spoon since you may well not get the correct dose.
By way of example, quite a few claimed scenarios of death happened from the submit-operative period of time subsequent tonsillectomy and/or adenoidectomy, and lots of of the kids had proof of remaining ultra-immediate metabolizers of codeine. In addition, youngsters with obstructive snooze apnea who're addressed with codeine for article-tonsillectomy and/or adenoidectomy pain may be significantly delicate to its respiratory depressant result. As a result of possibility of lifetime-threatening respiratory depression and death:
Just take this medication accurately as prescribed to lower the chance of addiction. Question your medical professional or pharmacist For additional information.
CONDITIONS OF USE: The knowledge With this databases is intended to supplement, not substitute for, the knowledge and judgment of healthcare experts. The data will not be intended to deal with all achievable takes advantage of, Instructions, precautions, drug interactions or adverse results, nor should it be construed to point that usage of a selected drug is safe, correct or successful for you or any individual else.
This drugs isn't for coughs because of smoking cigarettes or lung sickness. You could get sunburned a lot more very easily. Avoid Sunlight, sunlamps, and tanning beds. Use sunscreen and have on apparel and eyewear that shields you within the Sunlight. For anyone who is sixty five or more mature, use promethazine and codeine with treatment. You could have additional Unwanted effects. The prospect of very negative Unwanted effects may very well be greater in youngsters. This may be much more probable to occur in little ones who definitely have respiratory problems. Fatal respiratory complications have took place with the use of codeine in some kids. Talk with the physician. Inform your physician In case you are pregnant or prepare on acquiring Expecting. You need to talk about the advantages and risks of working with promethazine and codeine when you are Expecting. Employing promethazine and codeine for a long period throughout pregnancy may perhaps bring about withdrawal inside the new child infant. This can be lifestyle-threatening. Converse with the medical doctor. How Is that this medication (Promethazine and Codeine) finest taken?
A potentially lethal symptom advanced in some cases generally known as Neuroleptic Malignant Syndrome (NMS) continues to be noted in association with promethazine HCl by yourself or in combination with antipsychotic medications.
Usually do not flush down a rest room or pour down a drain Unless of course that you are explained to to do so. Verify with your pharmacist In case you have questions about The obvious way to toss out medications. There may be drug just take-again applications in your area. Purchaser Data Use and Disclaimer
Examine the Medication Manual furnished by your pharmacist Before you begin taking promethazine/phenylephrine/codeine and each time you can get a refill. If you have any queries, request your health practitioner or pharmacist.
Propulsive peristaltic waves from the colon are diminished, even though tone could possibly be greater to The purpose of spasm causing constipation. Other opioid-induced outcomes may contain a reduction in biliary and pancreatic secretions, spasm of sphincter of Oddi, and transient elevations in serum amylase.
Codeine results in miosis, even in complete darkness. Pinpoint pupils are an indication of opioid overdose but are not pathognomonic (eg, pontine check here lesions of hemorrhagic or ischemic origins could create comparable findings). Marked mydriasis as an alternative to miosis can be found because of hypoxia in overdose cases.
Codeine: Narcotic analgesics, together with codeine, exert their Key effects on the central anxious process and gastrointestinal tract. The analgesic effects of codeine are resulting from its central motion; nonetheless, the exact internet sites of action have not been identified, and also the mechanisms concerned look like pretty complex.
The Promethazine VC with Codeine manufacturer identify has long been discontinued in the U.S. If generic variations of the product or service have been authorized by the FDA, there might be generic equivalents available.
The effects of concomitant use or discontinuation of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with codeine are advanced.